Uniform Fe₃O₄/Gd₂O₃-DHCA nanocubes for dual-mode magnetic resonance imaging

• Miao Qin,
• Yueyou Peng,
• Mengjie Xu,
• Hui Yan,
• Yizhu Cheng,
• Xiumei Zhang,
• Di Huang,
• Weiyi Chen and
• Yanfeng Meng

Beilstein J. Nanotechnol. 2020, 11, 1000–1009, doi:10.3762/bjnano.11.84

• -dihydroxyhydrocinnamic acid (DHCA); dual-mode imaging; Fe3O4/Gd2O3-DHCA nanocubes; gadolinium oxide (Gd2O3); iron(II,III) oxide (Fe3O4); magnetic resonance imaging (MRI); Introduction Magnetic resonance imaging (MRI) is a noninvasive technique that has been broadly used in the clinical field to assist in disease

Extracellular biosynthesis of gadolinium oxide (Gd₂O₃) nanoparticles, their biodistribution and bioconjugation with the chemically modified anticancer drug taxol

• Shadab Ali Khan,
• Sanjay Gambhir and
• Absar Ahmad

Beilstein J. Nanotechnol. 2014, 5, 249–257, doi:10.3762/bjnano.5.27

• treatment of cancer, we first synthesized extracellular, protein-capped, highly stable and well-dispersed gadolinium oxide (Gd2O3) nanoparticles by using thermophilic fungus Humicola sp. The biodistribution of the nanoparticles in rats was checked by radiolabelling with Tc-99m. Finally, these nanoparticles

• spectra was performed by using the Shirley algorithm. The chemically distinct species were resolved by a nonlinear least square fitting procedure. Radiolabelling and biodistribution studies Radiolabelling of gadolinium oxide (Gd2O3) nanoparticles with Tc-99m To fabricate Tc-99m–Gd2O3 nanoparticles, 10 mg

• biodistribution of the complex (Tc-99m–Gd nanoparticle), these Gd2O3 nanoparticles were taken up in the liver, heart, kidneys and cleared through urine within 45 min. Figure 6A and 6B show the UV–vis analyses of gadolinium oxide nanoparticles and Gd2O3–taxol bioconjugate, respectively. Gadolinium oxide (Gd2O3